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KMID : 1189420030160020079
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2003 Volume.16 No. 2 p.79 ~ p.95
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The Study on Depigmentation Effects of Salt, Acetum, Sesami Semen Nigrum
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Cho Jae-Hoon
Kim Hae-Jung
Kim Yoon-Bum
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Abstract
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Objectives: This study was performed to investigate the depigmentation effects of Salt, Acetum, Sesami Semen Nigrum.
Methods: Inhibition of tyrosinase activity, melanin production & cell viability in cultured B16 melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide were measured.
Results: Salt, Acetum, Sesami Semen Nigrum did not show any inhibitory effects of tyrosinase activity & melanin production in melanoma cells, UV screen and cytoprotective effects on PC12 cells injured by hydrogen peroxide.
Conclusions: This study shows that Salt, Acetum, Sesami Semen Nigrum which were generally used for the addition in external application do not have the depigmentation effects. Following this, the depigmentation effects of the other addition which were generally used for external application shoud be examined.
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KEYWORD
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Salt , Acetum , Sesami Semen Nigrum , Depigmentation , Tyrosinase , Melanin , UV , Cytoprotective
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